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Invitrogen™ Human SIRT5 Synthetic Peptide
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Mængde:
50 μg
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50µg
Beschreibung
SIRT5 Synthetic Peptide, PEP-1080, from Invitrogen.
SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
Spezifikation
Spezifikation
| Gen-id (Entrez) | 23408 |
| Arter | Human |
| Oprensningsmetode | purified |
| Adgangsnummer | Q9NXA8 |
| Fælles navn | Human SIRT5 |
| Koncentration | 200 μg/mL |
| Indhold og opbevaring | -20°C |
| Oversigt | Synthetic Peptide |
| Format | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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