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Invitrogen™ Human SIK2 Synthetic Peptide

Artikelnummer. 15215259
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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Artikelnummer. Mængde unitSize
15215259 50 μg 50µg
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Artikelnummer. 15215259 Leverandør Invitrogen™ Leverandørnr. PEP1254

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Beskrivelse

Synthetic Peptide

This peptide corresponds to 16 amino acids near the center of human SIK2. PEP-1254 can be used as a blocking peptide with polyclonal antibody PA5-34339.

SNF1LK2 (QIK) is a serine/threonine kinase and is a salt-inducible kinase that belongs to the AMP-activated protein kinase family. SNF1LK2 negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1'alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 23235
Arter Human
Oprensningsmetode purified
Adgangsnummer Q9H0K1
Fælles navn SIK2
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gene Alias G630080D20Rik; KIAA0781; LOH11CR1I; QIK; Qin-induced kinase; RGD1559698; salt induceable kinase 2; salt inducible kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; SIK-2; SNF1-like kinase 2; SNF1LK2
Gen symbol SIK2
Lyofiliseret, frysetørret No
Konserveringsmiddel Sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO
Opbevaringsbuffer PBS
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