missing translation for 'onlineSavingsMsg'
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Invitrogen™ Human RNF7 (aa 31-113) Control Fragment Recombinant Protein
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Mængde:
100 μL
Beskrivelse
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57906 (PA5-57906. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Tekniske data
Tekniske data
| Adgangsnummer | Q9UBF6 |
| Koncentration | ≥5.0 mg/mL |
| Til brug med (applikation) | Blocking Assay, Control |
| Formulering | 1 M urea, PBS with no preservative; pH 7.4 |
| Gen-id (Entrez) | 9616 |
| Navn | Human RNF7 (aa 31-113) Control Fragment |
| Mængde | 100 μL |
| Regulatorisk status | RUO |
| Gene Alias | CKBBP1; CKII beta-binding protein 1; OTTHUMP00000180645; rbx2; Regulator of cullins 2; ring finger protein 7; RING-box protein 2; RNF7; ROC2; SAG; Sensitive to apoptosis gene protein; sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2; zinc RING finger protein SAG |
| Fælles navn | RNF7 |
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