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Invitrogen™ Human RAB7 (aa 84-199) Control Fragment Recombinant Protein
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Mængde:
100 μL
Beskrivelse
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52369 (PA5-52369. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Tekniske data
Tekniske data
| Adgangsnummer | P51149 |
| Koncentration | ≥5.0 mg/mL |
| Til brug med (applikation) | Blocking Assay, Control |
| Formulering | 1 M urea, PBS with no preservative; pH 7.4 |
| Gen-id (Entrez) | 7879 |
| Navn | Human RAB7 (aa 84-199) Control Fragment |
| Mængde | 100 μL |
| Regulatorisk status | RUO |
| Gene Alias | GTP-binding protein (rab7); hypothetical protein LOC509970; PRO2706; RAB7; rab-7; RAB7, member RAS oncogene family; Rab7a; RAB7A, member RAS oncogene family; Ras-associated protein RAB7; ras-related protein BRL-RAS; Ras-related protein p23; ras-related protein Rab-7 A |
| Fælles navn | RAB7 |
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