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Invitrogen™ Human PRR5L Synthetic Peptide
Beskrivelse
PRR5L Synthetic Peptide, PEP-1243, from Invitrogen.
Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.
Tekniske data
Tekniske data
| Gen-id (Entrez) | 79899 |
| Arter | Human |
| Oprensningsmetode | purified |
| Adgangsnummer | Q6MZQ0 |
| Fælles navn | Human PRR5L |
| Koncentration | 200 μg/mL |
| Indhold og opbevaring | -20°C |
| Oversigt | Synthetic Peptide |
| Format | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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Produkttitel
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