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Invitrogen™ Human PRAS40 Synthetic Peptide

Artikelnummer. 15215539
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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15215539 50 μg 50µg
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Artikelnummer. 15215539 Leverandør Invitrogen™ Leverandørnr. PEP1608

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Beskrivelse

Synthetic Peptide

This peptide corresponds to 19 amino acids near the carboxy terminus of human AKT1S1. PEP-1608 can be used as a blocking peptide with polyclonal antibody PA5-34565. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.

The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can induce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 84335
Arter Human
Oprensningsmetode purified
Adgangsnummer Q96B36
Fælles navn PRAS40
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gene Alias 1110012J22Rik; 40 kDa proline-rich AKT substrate; AI227026; AKT1 substrate 1; AKT1 substrate 1 (proline rich); AKT1 substrate 1 (proline-rich); akt1s1; Lobe; Lobel; OTTHUMP00000196756; OTTHUMP00000196760; PKB/Akt substrate 40; Pras; PRAS40; Proline-rich AKT substrate; proline-rich AKT1 substrate 1
Gen symbol AKT1S1
Lyofiliseret, frysetørret No
Konserveringsmiddel Sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO
Opbevaringsbuffer PBS
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