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Invitrogen™ Human PHAP Synthetic Peptide

Artikelnummer. 15246369
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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15246369 50 μg 50µg
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Artikelnummer. 15246369 Leverandør Invitrogen™ Leverandørnr. PEP0143

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Beskrivelse

Synthetic Peptide

PHAP Synthetic Peptide, PEP-0143, from Invitrogen.

Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 8125
Arter Human
Oprensningsmetode purified
Adgangsnummer P39687
Fælles navn Human PHAP
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gen symbol ANP32A
Lyofiliseret, frysetørret No
Konserveringsmiddel 0.02% sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO - research use only
Opbevaringsbuffer PBS
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