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Gibco™ Human PDGF-AB Recombinant Protein, PeproTech®

Artikelnummer. p-7246260
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Mængde:
1 mg
10 μg
100 μg
2 μg
250 μg
50 μg
500 μg
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Artikelnummer. 17801763

Brand: Gibco™ 10000AB100UG

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Beskrivelse

Recombinant Protein

Recombinant Human PDGF-AB is a 26.4 kDa disulfide-linked dimer, consisting of one alpha chain and one beta chain (234 total amino acids). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P01127, P04085
Til brug med (applikation) Functional Assay
Formulering protein with no preservative
Gen-id (Entrez) 5154, 5155
Molekylvægt (g/mol) 26.4 kDa
Navn Human PDGF-AB
Mængde 100 μg
Kilde E. coli
Regulatorisk status RUO
Endotoksin koncentration <1 EU/ μg
Gene Alias Becaplermin; c-sis; H-PDGF-AB; IBGC5; PDGF A-chain; PDGF subunit A; PDGF subunit B; PDGF, B chain; PDGF1; PDGF-1; PDGF2; PDGF-2; Pdgfa; PDGF-A; PDGFAB; PDGFB; PDGF-B; platelet derived growth factor subunit A; platelet derived growth factor subunit B; platelet derived growth factor, alpha; platelet derived growth factor, B polypeptide; platelet-derived growth factor 2; platelet-derived growth factor A chain; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide; Platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); platelet-derived growth factor subunit A; Platelet-derived growth factor subunit B; platelet-derived growth factor, beta polypeptide (oncogene SIS); proto-oncogene c-Sis; SIS; SSV
Fælles navn PDGF-AB
Gen symbol PDGFA, PDGFB
Biologisk aktivitet The ED50 as determined by the dose-dependent stimulation of thymidine uptake by Balb/c 3T3 cells is ≤ 1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens Alpha chain: SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT Beta chain: SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT
Indhold og opbevaring -20°C
Udtrykssystem E. coli
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 98% by SDS-PAGE gel and HPLC analyses.
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