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Invitrogen™ Human Osteopontin Synthetic Peptide

Artikelnummer. 15255549
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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Artikelnummer. Mængde unitSize
15255549 50 μg 50µg
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Artikelnummer. 15255549 Leverandør Invitrogen™ Leverandørnr. PEP1622
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Forventet forsendelse: 05-08-2026
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Beskrivelse

Synthetic Peptide

This peptide corresponds to 18 amino acids near the amino terminus of SPP1. PEP-1622 can be used as a blocking peptide with polyclonal antibody PA5-34579. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.

Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 6696
Arter Human
Oprensningsmetode purified
Adgangsnummer P10451
Fælles navn Osteopontin
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gene Alias 2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bone sialoprotein 1 (BSPI/BSP1); Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; CALPHA1 fusion; Early T lymphocyte activation 1 (ETA1); early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; immunoglobulin alpha 1 heavy chain constant region fusion protein; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1 (SPP1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); SPP1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin
Gen symbol SPP1
Lyofiliseret, frysetørret No
Konserveringsmiddel Sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO
Opbevaringsbuffer PBS
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