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R&D Systems™ Human NKG2A/CD159a (NP_002250) VersaClone cDNA
Beskrivelse
- KLRC1 killer cell lectin like receptor C1 [ Homo sapiens (human) ]
- Also known as: NKG2; NKG2A; CD159A
- NKG2A and NKG2C are type II transmembrane proteins with extracellular C-type lectin domains.
- These proteins heterodimerize with CD94 to form complexes that recognize HLA-E as ligand.
- The NKG2A/CD94 complex delivers an inhibitory signal resulting from ITIMs within the NKG2A cytoplasmic domain.
- NKG2C/CD94 provides an activating signal due to association with the ITAM-containing DAP12 adapter protein.
- These complexes are expressed on NK and T cell subsets.
- The NKG2A/CD159a/KLRC1 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
- For reasearch use only. Not for use in humans.
Tekniske data
Tekniske data
| Gene | hKLRC1 |
| Adgangsnummer | NP_002250 |
| Koncentration | 10 μg at 0.2 μg/μL |
| Formulering | cDNA is provided in 10 mM Tris-Cl, pH 8.5 |
| Indsæt type | 715 bp |
| Gen-id (Entrez) | 3821 |
| Indhold og opbevaring | Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Arter | Human |
| Mængde | 10 μg |
Produkttitel
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