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Invitrogen™ Human LRRTM3 Synthetic Peptide

Artikelnummer. 15295209
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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15295209 50 μg 50µg
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Artikelnummer. 15295209 Leverandør Invitrogen™ Leverandørnr. PEP1212

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Beskrivelse

Synthetic Peptide

LRRTM3 Synthetic Peptide, PEP-1212, from Invitrogen.

The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the A-beta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma A-beta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 347731
Arter Human
Oprensningsmetode purified
Adgangsnummer Q86VH5
Fælles navn Human LRRTM3
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gen symbol LRRTM3
Lyofiliseret, frysetørret No
Konserveringsmiddel 0.02% sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO - research use only
Opbevaringsbuffer PBS
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