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Invitrogen™ Human IRF8 Synthetic Peptide
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Mængde:
50 μg
Pakningsstørrelse:
50µg
Beskrivelse
IRF8 Synthetic Peptide, PEP-0206, from Invitrogen.
IRF8 (interferon regulatory factor 8) is a transcriptional activator or repressor. It specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes. IRF8 plays a negative regulatory role in cells of the immune system. It is involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells. This leads to recognition of AICE sequence, an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of the genes. Mutations in the gene can result in immunodeficiencey 32A and 32B.
Tekniske data
Tekniske data
| Gen-id (Entrez) | 3394 |
| Arter | Human |
| Oprensningsmetode | purified |
| Adgangsnummer | Q02556 |
| Fælles navn | Human IRF8 |
| Koncentration | 200 μg/mL |
| Indhold og opbevaring | -20°C |
| Oversigt | Synthetic Peptide |
| Format | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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