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Invitrogen™ Human HTRA2 Synthetic Peptide

Artikelnummer. 15206409
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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15206409 50 μg 50µg
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Artikelnummer. 15206409 Leverandør Invitrogen™ Leverandørnr. PEP0183
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Forventet forsendelse: 19-08-2026
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Beskrivelse

Synthetic Peptide

This peptide corresponds to 15 amino acids near the carboxy terminus of human OMI. PEP-0183 can be used as a blocking peptide with polyclonal antibody PA5-20064.

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3). Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4). Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 27429
Arter Human
Oprensningsmetode purified
Adgangsnummer O43464
Fælles navn HTRA2
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gene Alias AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI
Gen symbol HTRA2
Lyofiliseret, frysetørret No
Konserveringsmiddel Sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO
Opbevaringsbuffer PBS
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