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Invitrogen™ Human HINT1 Synthetic Peptide

Artikelnummer. 15328950
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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15328950 50 μg 50µg
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Artikelnummer. 15328950 Leverandør Invitrogen™ Leverandørnr. PEP0733

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Synthetic Peptide

This peptide corresponds to 17 amino acids near the center of human HINT1. PEP-0733 can be used as a blocking peptide with polyclonal antibody PA5-20613.

Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 3094
Arter Human
Oprensningsmetode purified
Adgangsnummer P49773
Fælles navn HINT1
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gene Alias 17 kDa inhibitor of protein kinase C; AA673479; Adenosine 5'-monophosphoramidase; FLJ30414; FLJ32340; HINT; Hint1; histidine triad nucleotide binding protein 1; histidine triad nucleotide-binding protein 1; Ipk1; NMAN; PKC inhibitor/ interacting protein; Pkci; PKCI1; PKCI-1; Prkci; PRKCNH1; protein kinase C inhibitor 1; protein kinase C, iota; protein kinase C-interacting protein 1
Gen symbol Hint1
Lyofiliseret, frysetørret No
Konserveringsmiddel Sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO
Opbevaringsbuffer PBS
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