missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Rekombinante proteiner
  4. Gibco™ Human GDF-15/MIC-1 Recombinant Protein, PeproTech®

Gibco™ Human GDF-15/MIC-1 Recombinant Protein, PeproTech®

Artikelnummer. 17861363
Klik for at se tilgængelige muligheder
Mængde:
1 mg
100 μg
20 μg
250 μg
5 μg
500 μg
Denne vare kan ikke returneres. Se returpolicy

Artikelnummer. 17861363

Brand: Gibco™ 12028C5UG

Venligst for at købe denne vare. Brug for en webkonto? Register dig hos os i dag!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Recombinant Protein

Recombinant Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 112 amino acid polypeptide chains. The calculated molecular weight of Recombinant Human GDF-15/MIC-1 is 24.6 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q99988
Til brug med (applikation) Functional Assay
Formulering protein with no preservative
Gen-id (Entrez) 9518
Molekylvægt (g/mol) 24.6 kDa
Navn Human GDF-15/MIC-1
Mængde 5 μg
Kilde CHO cells
Regulatorisk status RUO
Endotoksin koncentration <1 EU/ μg
Gene Alias Gdf15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; SBF
Fælles navn GDF15
Gen symbol Gdf15
Biologisk aktivitet Determined by its ability to inhibit alkaline phosphatase activity in differentiating MC3T3/E1 osteoblastcells. The expected ED50 for this effect is 75-200 ng/ml
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens ARNGDHCPLG PGRCCRLHTV RASLEDLGWA DWVLSPREVQ VTMCIGACPS QFRAANMHAQ IKTSLHRLKP DTVPAPCCVP ASYNPMVLIQ KTDTGVSLQT YDDLLAKDCH CI
Indhold og opbevaring -20°C
Udtrykssystem CHO cells
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 95% by SDS-PAGE gel and HPLC analyses.
Vis mere Vis mindre
Korrektion af produktindhold

Dit input er vigtigt for os. Udfyld denne formular for at give feedback relateret til indholdet på dette produkt.

Produkttitel

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.

Mange tak! Din feedback er blevet sendt. Hos Fisher Scientific arbejder vi altid på at forbedre vores indhold for dig. Vi sætter pris på din feedback.