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Gibco™ Human GASP-1 Recombinant Protein, PeproTech® Product Code.: 17840303
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Gibco™ Human GASP-1 Recombinant Protein, PeproTech®

Product Code. 17840303
500 μg, 500µg
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Quantity:
1 mg
100 μg
25 μg
250 μg
5 μg
500 μg
Unit Size:
100µg
1mg
250µg
25µg
500µg
5µg
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Product Code. 17840303

Brand: Gibco™ 12041500UG

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This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66 kDa by SDS-PAGE analysis under non-reducing conditions. The calculated molecular weight of Recombinant Human GASP-1 is 59.9 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-beta binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8TEU8
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 124857
Molecular Weight (g/mol) 59.9 kDa
Name Human GASP-1
Quantity 500 μg
Source CHO cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias 2610304F08Rik; AY100450; Gasp1; GASP-1; Growth and differentiation factor-associated serum protein 1; hGASP-1; mGASP-1; multivalent protease inhibitor protein; RGD1305361; UNQ9235/PRO31996; WAP four-disulfide core domain 20 B; WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein; WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2; WAP, FS, Ig, two KU and NTR module related protein; WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2; WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; WFDC20B; WFIKKN2; WFIKKN-related protein; WFIKKNRP
Common Name GASP1
Gene Symbol WFIKKN2
Biological Activity Determined by its ability to inhibit human Myostatin (GDF-8) activity in MCP-11 cells. The ED50 for this effect is 0.0025-0.0040 ug/ml in the presence of 5 ng/ml of human Myostatin (GDF-8).
Conjugate Unconjugated
Recombinant Recombinant
Sequence LPPIRYSHAG ICPNDMNPNL WVDAQSTCRR ECETDQECET YEKCCPNVCG TKSCVAARYM DVKGKKGPVG MPKEATCDHF MCLQQGSECD IWDGQPVCKC KDRCEKEPSF TCASDGLTYY NRCYMDAEAC SKGITLAVVT CRYHFTWPNT SPPPPETTMH PTTASPETPE LDMAAPALLN NPVHQSVTMG ETVSFLCDVV GRPRPEITWE KQLEDRENVV MRPNHVRGNV VVTNIAQLVI YNAQLQDAGI YTCTARNVAG VLRADFPLSV VRGHQAAATS ESSPNGTAFP AAECLKPPDS EDCGEEQTRW HFDAQANNCL TFTFGHCHRN LNHFETYEAC MLACMSGPLA ACSLPALQGP CKAYAPRWAY NSQTGQCQSF VYGGCEGNGN NFESREACEE SCPFPRGNQR CRACKPRQKL VTSFCRSDFV ILGRVSELTE EPDSGRALVT VDEVLKDEKM GLKFLGQEPL EVTLLHVDWA CPCPNVTVSE MPLIIMGEVD GGMAMLRPDS FVGASSARRV RKLREVMHKK TCDVLKEFLG LH
Content And Storage -20°C
Expression System CHO cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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