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Gibco™ Human Galectin-3 Recombinant Protein, PeproTech®

Artikelnummer. 17864003
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Mængde:
1 mg
10 μg
100 μg
250 μg
50 μg
500 μg
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Artikelnummer. 17864003

Brand: Gibco™ 4503850UG

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Beskrivelse

Recombinant Protein

Recombinant Human Galectin-3 is a globular 26.0 kDa protein containing 249 amino acid residues, but no disulfide bonds. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P17931
Til brug med (applikation) ELISA, Functional Assay, Western Blot
Formulering protein with no preservative
Gen-id (Entrez) 3958
Molekylvægt (g/mol) 26 kDa
Navn Human Galectin-3
Mængde 50 μg
Kilde E. coli
Regulatorisk status RUO
Endotoksin koncentration <1 EU/ μg
Gene Alias 35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen
Fælles navn Galectin 3
Gen symbol LGALS3
Biologisk aktivitet Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 ug/ml with a peak response obtained (at 250 ug/ml)
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens ADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYHGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSAPGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SKLGISGDID LTSASYTMI
Indhold og opbevaring -20°C
Udtrykssystem E. coli
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 98% by SDS-PAGE gel and HPLC analyses.
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