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Gibco™ Human FRP-5 (soluble) Recombinant Protein, PeproTech®

Artikelnummer. 17800653
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Artikelnummer. Mængde
17800653 100 μg
17889992 10 μg
17821443 1 mg
17871023 250 μg
17830183 500 μg
17811333 50 μg
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Artikelnummer. 17800653 Leverandør Gibco™ Leverandørnr. 12053100UG
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    2129.80 DKK / 100µg
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Forventet forsendelse: 04-12-2026
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Beskrivelse

Recombinant Protein

PeproTech's CHO cell-derived Recombinant Human sFRP5 is a 288-amino-acid length glycoprotein with a calculated molecular weight of 32.7 kDa; however, due to glycosylation, protein migration occurs at an apparent molecular weight of approximately 33-35 kDa by SDS-PAGE analysis under both reducing and non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q5T4F7
Til brug med (applikation) Bioactivity, Control
Formulering Protein with no preservative
Gen-id (Entrez) 6425
Molekylvægt (g/mol) 32.7 kDa
Navn Human FRP-5 (soluble)
Oprensningsmetode Purified
Mængde 100 μg
Kilde CHO cells
Opbevaringskrav -20°C
Regulatorisk status RUO
Endotoksin koncentration <1 EU/μg
Gene Alias AI605071; Frizzled-related protein 1b; FRP1B; FRP-1b; SARP3; SARP-3; secreted apoptosis related protein 3; secreted apoptosis-related protein 3; secreted frizzled related protein 5; secreted frizzled-related protein 5; secreted frizzled-related sequence protein 5; SFRP5; sFRP-5
Fælles navn SFRP5
Gen symbol SFRP5
Biologisk aktivitet Determined by its ability to decrease alkaline phosphatase activity in CCL-226 cells when treated with 25 ng/ml of Murine Wnt-3 a.
Produkttype Protein
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens EEYDYYGWQA EPLHGRSYSK PPQCLDIPAD LPLCHTVGYK RMRLPNLLEH ESLAEVKQQA SSWLPLLAKR CHSDTQVFLC SLFAPVCLDR PIYPCRSLCE AVRAGCAPLM EAYGFPWPEM LHCHKFPLDN DLCIAVQFGH LPATAPPVTK ICAQCEMEHS ADGLMEQMCS SDFVVKMRIK EIKIENGDRK LIGAQKKKKL LKPGPLKRKD TKRLVLHMKN GAGCPCPQLD SLAGSFLVMG RKVDGQLLLM AVYRWDKKNK EMKFAVKFMF SYPCSLYYPF FYGAAEPH
Indhold og opbevaring -20°C
Aktivitet Determined by its ability to decrease alkaline phosphatase activity in CCL-226 cells when treated with 25 ng/ml of Murine Wnt-3a.
Udtrykssystem CHO cells
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 98% by SDS-PAGE gel and HPLC analyses.
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