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Gibco™ Human Flt-3 Ligand (FLT3L) Recombinant Protein, PeproTech®

Artikelnummer. 17830243
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Mængde:
1 mg
10 μg
100 μg
2 μg
250 μg
50 μg
500 μg
Pakningsstørrelse:
10µg
50µg
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Artikelnummer. 17830243

Brand: Gibco™ 30019100UG

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4010.50 DKK valid until 2025-12-19
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Beskrivelse

Recombinant Protein

Recombinant Human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P49771
Til brug med (applikation) ELISA, Functional Assay, Western Blot
Formulering protein with no preservative
Gen-id (Entrez) 2323
Molekylvægt (g/mol) 17.6 kDa
Navn Human Flt-3 Ligand (FLT3L)
Mængde 100 μg
Kilde E. coli
Regulatorisk status RUO
Endotoksin koncentration <1 EU/ μg
Gene Alias FL; Flt 3 ligand; Flt3; Flt3 L; Flt3 ligand; Flt3l; Flt3lg; fms related receptor tyrosine kinase 3 ligand; fms related tyrosine kinase 3 ligand; FMS-like tyrosine kinase 3 ligand; fms-related tyrosine kinase 3; fms-related tyrosine kinase 3 ligand; H-FLT-3-L; Ly72L; M-FLT-3-L; NEWGENE_2322792; SL cytokine
Fælles navn FLT3LG
Gen symbol FLT3LG
Biologisk aktivitet The ED50 was determined by the dose-dependent stimulation of the proliferation of human AML5 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
Indhold og opbevaring -20°C
Udtrykssystem E. coli
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 98% by SDS-PAGE gel and HPLC analyses.
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