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Gibco™ Human FGF-18 Recombinant Protein, PeproTech®

Artikelnummer. 17801063
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Mængde:
1 mg
100 μg
25 μg
250 μg
5 μg
500 μg
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Artikelnummer. 17801063

Brand: Gibco™ 10028100UG

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Beskrivelse

Recombinant Protein

Recombinant Human FGF-18 derived from E.coli is a 20.1 kDa protein consisting of 173 amino acid residues, resulting from C-terminal truncation of the full length protein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer O76093
Til brug med (applikation) Functional Assay
Formulering protein with no preservative
Gen-id (Entrez) 8817
Molekylvægt (g/mol) 20.1 kDa
Navn Human FGF-18
Mængde 100 μg
Kilde E. coli
Regulatorisk status RUO
Endotoksin koncentration <1 EU/ μg
Gene Alias D130055P09Rik; FGF; FGF18; FGF-18; Fibroblast growth factor; Fibroblast growth factor 18; UNQ420/PRO856; zFGF5
Fælles navn FGF18
Gen symbol Fgf18
Biologisk aktivitet Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 10^5 units/mg
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens AEENVDFRIH VENQTRARDD VSRKQLRLYQ LYSRTSGKHI QVLGRRISAR GEDGDKYAQL LVETDTFGSQ VRIKGKETEF YLCMNRKGKL VGKPDGTSKE CVFIEKVLEN NYTALMSAKY SGWYVGFTKK GRPRKGPKTR ENQQDVHFMK RYPKGQPELQ KPFKYTTVTK RSR
Indhold og opbevaring -20°C
Udtrykssystem E. coli
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 95% by SDS-PAGE gel and HPLC analyses.
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