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Gibco™ Human FGF-10 Recombinant Protein, PeproTech®

Artikelnummer. 17841463
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Mængde:
100 μg
2 x 500 μg
25 μg
250 μg
5 μg
50 μg
500 μg
Pakningsstørrelse:
100µg
250µg
25µg
500µg
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Artikelnummer. 17841463

Brand: Gibco™ 10026100UG

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Recombinant Protein

100-00CC-500UG will be provided as 2 x 250 μg (100-00CC-250UG). Recombinant Human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer O15520
Til brug med (applikation) ELISA, Functional Assay, Western Blot
Formulering protein with no preservative
Gen-id (Entrez) 2255
Molekylvægt (g/mol) 19.3 kDa
Navn Human FGF-10
Mængde 100 μg
Kilde E. coli
Regulatorisk status RUO
Endotoksin koncentration <1 EU/ μg
Gene Alias AEY17; BB213776; FGF; Fgf10; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Gsfaey17; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
Fælles navn FGF10
Gen symbol FGF10
Biologisk aktivitet Assay 1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10^6 units/mg Assay 2: Determined by a cell proliferation assay using 4 MBr-5 cells. The expected ED50 for this effect is 0.5-15.0 ng/ml
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS
Indhold og opbevaring -20°C
Udtrykssystem E. coli
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 95% by SDS-PAGE gel and HPLC analyses.
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