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R&D Systems™ Human DAP12 (NP_003323) VersaClone cDNA
Beskrivelse
- TYROBP TYRO protein tyrosine kinase binding protein [ Homo sapiens (human) ]
- Also known as: DAP12; KARAP; PLOSL
- The DAP12 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
- DAP12 is a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain.
- It may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element.
- DAP12 may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation.
- Alternatively spliced transcripts encoding different proteins have been described.
- For reasearch use only. Not for use in humans.
Tekniske data
Tekniske data
| Gene | hTYROBP |
| Adgangsnummer | NP_003323 |
| Koncentration | 10 μg at 0.2 μg/μL |
| Formulering | cDNA is provided in 10 mM Tris-Cl, pH 8.5 |
| Indsæt type | 355 bp |
| Gen-id (Entrez) | 7305 |
| Indhold og opbevaring | Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
| Arter | Human |
| Produktlinje | R&D Systems |
| Mængde | 10 μg |
Produkttitel
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