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Invitrogen™ Human CRIM2 Synthetic Peptide
Beskrivelse
This peptide corresponds to 15 amino acid peptide near the carboxy terminus of human CRIM2. PEP-1453 can be used as a blocking peptide with polyclonal antibody PA5-34411.
CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-Beta1, suppressing activin- and TGF-Beta1-dependent transcription.
Tekniske data
Tekniske data
| Gen-id (Entrez) | 375616 |
| Arter | Human |
| Oprensningsmetode | purified |
| Adgangsnummer | Q6ZWJ8 |
| Fælles navn | CRIM2 |
| Koncentration | 200 μg/mL |
| Indhold og opbevaring | -20°C |
| Oversigt | Synthetic Peptide |
| Format | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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Produkttitel
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