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Invitrogen™ Human CRIM1 Synthetic Peptide
Beskrivelse
This peptide corresponds to 17 amino acid peptide near the carboxy terminus of human Crim1. PEP-1452 can be used as a blocking peptide with polyclonal antibody PA5-34410.
CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
Tekniske data
Tekniske data
| Gen-id (Entrez) | 51232 |
| Arter | Human |
| Oprensningsmetode | purified |
| Adgangsnummer | Q9NZV1 |
| Fælles navn | CRIM1 |
| Koncentration | 200 μg/mL |
| Indhold og opbevaring | -20°C |
| Oversigt | Synthetic Peptide |
| Format | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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Produkttitel
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