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Invitrogen™ Human CDNF Synthetic Peptide

Artikelnummer. 15398680
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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15398680 50 μg 50µg
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Artikelnummer. 15398680 Leverandør Invitrogen™ Leverandørnr. PEP0547

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Beskrivelse

Synthetic Peptide

CDNF Synthetic Peptide, PEP-0547, from Invitrogen.

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6 OHDA) induced degeneration of dopaminergic neurons in a rat model of Parkinsons disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinsons disease. At least two isoforms of CDNF are known to exist.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 441549
Arter Human
Oprensningsmetode purified
Adgangsnummer Q49AH0
Fælles navn Human CDNF
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gen symbol CDNF
Lyofiliseret, frysetørret No
Konserveringsmiddel 0.02% sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO - research use only
Opbevaringsbuffer PBS
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