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Invitrogen™ Human CD177 Control Fragment Recombinant Protein
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Mængde:
100 μL
Beschreibung
Highest antigen sequence indentity to the following orthologs: Mouse (49%), Rat (49%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
Spezifikation
Spezifikation
| Adgangsnummer | Q8N6Q3 |
| Koncentration | ≥5.0 mg/mL |
| Til brug med (applikation) | Blocking Assay, Control |
| Formulering | 1 M urea, PBS with no preservative; pH 7.4 |
| Gen-id (Entrez) | 57126 |
| Navn | Human CD177 Control Fragment |
| Mængde | 100 μL |
| Regulatorisk status | RUO |
| Gene Alias | 1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2 A; Human neutrophil alloantigen 2 A; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181 |
| Fælles navn | CD177 |
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