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Invitrogen™ Human CCL3 (MIP-1 alpha) Recombinant Protein
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Mængde:
1 mg
Pakningsstørrelse:
1mg
Beskrivelse
This product contains purified recombinant human MIP-1a protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.
Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1alpha and MIP-1beta exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes, and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.
Tekniske data
Tekniske data
| Adgangsnummer | P10147 |
| Koncentration | 0.10 mg/mL |
| Til brug med (applikation) | Control, Western Blot |
| Formulering | 20 mM tris HCl with 50% glycerol and no preservative; pH 8 |
| Gen-id (Entrez) | 6348 |
| Navn | Human CCL3 (MIP-1 alpha) |
| Mængde | 1 mg |
| Kilde | E. Coli |
| Regulatorisk status | RUO |
| Gene Alias | AI323804; C-C motif chemokine 3; C-C motif chemokine ligand 3; CCL3; chemokine (C-C motif) ligand 3; G0/G1 switch regulatory protein 19-1; G0S19-1; Heparin-binding chemotaxis protein; H-MIP-1-alpha; L2G25B; LD78ALPHA; LD78-alpha; LD78-alpha(4-69); Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3); macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1 alpha; MIP1 (a); mip1 alpha; MIP-1 alpha; MIP1-(a); MIP1A; MIP-1 A; MIP-1 alpha; MIP-1-alpha; MIP1-alpha; MIP-1-alpha(4-69); PAT 464.1; RP23-320E6.7; Scya3; SIS-alpha; SIS-beta; small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1 A); small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; TY-5 |
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