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Invitrogen™ Human Btk Synthetic Peptide

Artikelnummer. 15266419
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Mængde:
50 μg
Pakningsstørrelse:
50µg
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15266419 50 μg 50µg
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Artikelnummer. 15266419 Leverandør Invitrogen™ Leverandørnr. PEP0203

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Synthetic Peptide

BTK Synthetic Peptide, PEP-0203, from Invitrogen.

Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9. The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens. BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.
TRUSTED_SUSTAINABILITY

Tekniske data

Gen-id (Entrez) 695
Arter Human
Oprensningsmetode purified
Adgangsnummer Q06187
Fælles navn Human Btk
Koncentration 200 μg/mL
Indhold og opbevaring -20°C
Oversigt Synthetic Peptide
Format Liquid
Formulering PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Til brug med (applikation) Blocking Assay, Control
Gen symbol BTK
Lyofiliseret, frysetørret No
Konserveringsmiddel 0.02% sodium azide
Produkttype Peptide
Mængde 50 μg
Regulatorisk status RUO - research use only
Opbevaringsbuffer PBS
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