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Invitrogen™ Human BRUCE Synthetic Peptide
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Mængde:
50 μg
Pakningsstørrelse:
50µg
Beskrivelse
BRUCE Synthetic Peptide, PEP-1454, from Invitrogen.
Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.
Tekniske data
Tekniske data
| Gen-id (Entrez) | 57448 |
| Arter | Human |
| Oprensningsmetode | purified |
| Adgangsnummer | Q9NR09 |
| Fælles navn | Human BRUCE |
| Koncentration | 200 μg/mL |
| Indhold og opbevaring | -20°C |
| Oversigt | Synthetic Peptide |
| Format | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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