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Gibco™ Human B7-1 Fc Recombinant Protein, PeproTech®
CHO cells Recombinant Protein
598.00 DKK - 8210.00 DKK
Specifications
| Accession Number | P33681 |
|---|---|
| For Use With (Application) | Functional Assay |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 941 |
| Molecular Weight (g/mol) | 50 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17882073
|
Gibco™
310-32-100UG |
100 μg |
1450.00 DKK
100µg |
Estimated Shipment: 11-06-2024 Log in to see stock. |
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|
17842563
|
Gibco™
310-32-1MG |
1 mg |
8210.00 DKK
1mg |
Estimated Shipment: 11-06-2024 Log in to see stock. |
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|
17822793
|
Gibco™
310-32-20UG |
20 μg |
598.00 DKK
20µg |
Estimated Shipment: 11-06-2024 Log in to see stock. |
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|
17852663
|
Gibco™
310-32-250UG |
250 μg |
2900.00 DKK
250µg |
Estimated Shipment: 11-06-2024 Log in to see stock. |
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|
17812083
|
Gibco™
310-32-500UG |
500 μg |
4915.00 DKK
500µg |
Estimated Shipment: 11-06-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.Specifications
| P33681 | |
| protein with no preservative | |
| 50 | |
| CHO cells | |
| RUO | |
| Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1 | |
| Human | |
| Recombinant | |
| Lyophilized |
| Functional Assay | |
| 941 | |
| Human B7-1 Fc | |
| -20°C | |
| <1 EU/μg | |
| CD80 | |
| Unconjugated | |
| VIHVTKEVKE VATLSCGHNV SVEELAQTRI YWQKEKKMVL TMMSGDMNIW PEYKNRTIFD ITNNLSIVIL ALRPSDEGTY ECVVLKYEKD AFKREHLAEV TLSVKADFPT PSISDFEIPT SNIRRIICST SGGFPEPHLS WLENGEELNA INTTVSQDPE TELYAVSSKL DFNMTTNHSF MCLIKYGHLR VNQTFNWNTT KQEHFPDNGG PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |