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Gibco™ Human APRIL Recombinant Protein, PeproTech®

Artikelnummer. p-7246320
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Mængde:
10 μg
2 μg
2 x 250 μg
2 x 50 μg
4 x 250 μg
5 x 50 μg
50 μg
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Artikelnummer. 17852333

Brand: Gibco™ 31010C100UG

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Beskrivelse

Recombinant Protein

310-10C-01M will be provided as 20 x 50 μg (310-10C-50UG). 310-10C-500 will be provided as 10 x 50 μg (310-10C-50UG). 310-10C-250 will be provided as 5 x 50 μg (310-10C-50UG). 310-10C-100 will be provided as 2 x 50 μg (310-10C-50UG) Recombinant human APRIL is a soluble 16.3 kDa protein, consisting of 146 amino acid residues. *Human APRIL (Catalog Number 310-10C) has replaced Human APRIL (Catalog Number 310-10). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer O75888
Til brug med (applikation) Control, Bioactivity
Formulering Protein with no preservative
Gen-id (Entrez) 8741
Molekylvægt (g/mol) 16.3 kDa
Navn Human APRIL
Oprensningsmetode Purified
Mængde 2 x 50 μg
Kilde Insect cells
Opbevaringskrav -20°C
Regulatorisk status RUO
Endotoksin koncentration <1 EU/μg
Gene Alias 2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2
Fælles navn APRIL
Gen symbol TNFSF13
Biologisk aktivitet Determined by its ability to induce NF-kappaB activation in HEK293-NF-kappaB reporter cells transfected with BCMA receptor.
Produkttype Protein
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL
Indhold og opbevaring -20°C
Aktivitet Determined by its ability to induce NF-kappaB activation in HEK293-NF-kappaB reporter cells transfected with BCMA receptor.
Udtrykssystem Insect cells
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 95% by SDS-PAGE gel and HPLC analyses.
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