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Invitrogen™ Human Amyloid Precursor Protein Synthetic Peptide
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Mængde:
50 μg
Pakningsstørrelse:
50µg
Beskrivelse
APP Synthetic Peptide, PEP-0851, from Invitrogen.
Amyloid Precursor Protein (APP) or Amyloid beta precursor protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. APP is important for neurite growth, neuronal adhesion and axonogenesis. APP is a 100-140 kDa transmembrane glycoprotein that exists as several isoforms resulting from alternative splicing. Proteolytic cleavage of APP by beta- and gamma-secretases results in the generation of beta amyloid, which is the primary component of senile plaques. Senile plaques are one of the major histopathologic features of Alzheimer's disease. Abnormal regulation and processing of APP also plays a role in Down's syndrome, early onset familial Alzheimer's disease, and cerebral hemorrhage.
Tekniske data
Tekniske data
| Gen-id (Entrez) | 351 |
| Arter | Human |
| Oprensningsmetode | purified |
| Adgangsnummer | P05067 |
| Fælles navn | Human Amyloid Precursor Protein |
| Koncentration | 200 μg/mL |
| Indhold og opbevaring | -20°C |
| Oversigt | Synthetic Peptide |
| Format | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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