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Invitrogen™ Human AGR2 Synthetic Peptide
Beskrivelse
This peptide corresponds to 17 amino acid peptide near the amino terminus of human AGR2. PEP-1560 can be used as a blocking peptide with polyclonal antibody PA5-34517. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).
Tekniske data
Tekniske data
| Gen-id (Entrez) | 10551 |
| Arter | Human |
| Oprensningsmetode | purified |
| Adgangsnummer | O95994 |
| Fælles navn | AGR2 |
| Koncentration | 200 μg/mL |
| Indhold og opbevaring | -20°C |
| Oversigt | Synthetic Peptide |
| Format | Liquid |
| Formulering | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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Produkttitel
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