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Invitrogen™ Human Activin A Recombinant Protein

Artikelnummer. 11538961
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Mængde:
1 mg
Pakningsstørrelse:
1mg
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Artikelnummer. 11538961

Brand: Invitrogen™ RP75637

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Beskrivelse

Recombinant Protein

RP-75637 contains purified recombinant human Inhibin beta A protein with an N-terminal hexahistidine tag. RP-75637 may be used as a positive control in many immunological assays.

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P08476
Koncentration 0.153 mg/mL
Til brug med (applikation) Control, Western Blot
Formulering tris HCl with 1 mM EDTA, 50% glycerol and no preservative; pH 8
Gen-id (Entrez) 3624
Navn Human Activin A
Mængde 1 mg
Kilde E. coli
Immunogen N/A
Regulatorisk status RUO
Gene Alias activin A; activin beta-A chain; BMP7; BMP-7; Bone morphogenetic protein 7; EDF; Eptotermin alfa; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FRP; FSH-releasing protein; INHB; Inhba; inhibin B subunit; inhibin beta A chain; inhibin beta A protein; inhibin beta A subunit; inhibin beta-A; inhibin beta-A-subunit; inhibin beta-subunit; inhibin subunit beta A; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1; OP1; OP-1; Osteogenic protein 1; unnamed protein product
Fælles navn Activin A
Gen symbol INHBA
Konjugeret Unconjugated
Arter E. coli
Rekombinant Recombinant
Protein tag His-tag
Sekvens Amino acids Gly311- Ser426 containing an N-terminal His-tag
Indhold og opbevaring -20°C, Avoid Freeze/Thaw Cycles
Udtrykssystem E. coli
Form Liquid
Protein undertype Recombinant
Renhed eller kvalitetsklasse >95%, by SDS-PAGE under reducing conditions
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