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Cytiva™ HiTrap™ Chromatography Columns with MabSelect™ VL Protein L Resin
Protein L affinity chromatography columns for capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
Brand: Cytiva™ 17542051
Additional Details : CAS Number : 64-17-5 Weight : 0.22000kg
Description
- Redesigned protein L ligand captures antibody Fabs, bispecifics, and other variants containing a kappa light chain with high binding capacity and improved alkaline stability
- High dynamic binding capacity for efficient capture of target molecules
- Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
- Provides good resolution for product-related impurities in the capture of bispecific antibodies
As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.
Specifications
| 1 mL | |
| 7 mm | |
| 1 in. | |
| <4 mL/min. | |
| Affinity Column |
| 0.3 in. | |
| 1 x 1 mL | |
| 25 mm | |
| 5 bar | |
| Antibody Affinity Chromatography |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- HiTrap MabSelect VL, 1 x 1 ml
Signal Word
- Warning
Hazard Category
- Flammable liquid Category 3
Hazard Statement
- H226-Flammable liquid and vapour.
Precautionary Statement
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : ethanol