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  7. Histamine dihydrochloride, 98+%, Thermo Scientific Chemicals

Histamine dihydrochloride, 98+%, Thermo Scientific Chemicals

Catalog Number p-7045037
Click to view available options
Quantity:
5 g
25 g
56-92-8
C5H11Cl2N3
184.06
MFCD00012703
PPZMYIBUHIPZOS-UHFFFAOYSA-N
histamine dihydrochloride, histamine 2hcl, 2-1h-imidazol-4-yl ethanamine dihydrochloride, 1h-imidazole-4-ethanamine dihydrochloride, 1h-imidazole-4-ethanamine, dihydrochloride, peremin, ceplene, 2-1h-imidazol-4-yl ethylamine dihydrochloride, 2-4-imidazolyl ethylamine dihydrochloride, histaminedium dichloride
5818
2-(1H-imidazol-5-yl)ethanamine;dihydrochloride
[H+].[H+].[Cl-].[Cl-].NCCC1=CN=CN1
56-92-8
C5H11Cl2N3
184.06
MFCD00012703
PPZMYIBUHIPZOS-UHFFFAOYSA-N
histamine dihydrochloride, histamine 2hcl, 2-1h-imidazol-4-yl ethanamine dihydrochloride, 1h-imidazole-4-ethanamine dihydrochloride, 1h-imidazole-4-ethanamine, dihydrochloride, peremin, ceplene, 2-1h-imidazol-4-yl ethylamine dihydrochloride, 2-4-imidazolyl ethylamine dihydrochloride, histaminedium dichloride
5818
2-(1H-imidazol-5-yl)ethanamine;dihydrochloride
[H+].[H+].[Cl-].[Cl-].NCCC1=CN=CN1

Description

Histamine dihydrochloride has been shown to activate nitric oxide synthetase and suppress or inhibit the generation of reactive oxygen species (ROS). Inhibition of ROS by histamine dihydrochloride allows activation of T cells and NK cells by IL-2. In a rat model, histamine dihydrochloride suppressed ROS generated by Kupffer cells through the H2 histamine receptor. It is a potent vasodilator and endogenous histamine receptor agonist.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Histamine dihydrochloride has been shown to activate nitric oxide synthetase and suppress or inhibit the generation of reactive oxygen species (ROS). Inhibition of ROS by histamine dihydrochloride allows activation of T cells and NK cells by IL-2. In a rat model, histamine dihydrochloride suppressed ROS generated by Kupffer cells through the H2 histamine receptor. It is a potent vasodilator and endogenous histamine receptor agonist.

Solubility
Very soluble in water and methanol. Soluble in ethanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. Store away from oxidizing agents. Store at 4°C.
TRUSTED_SUSTAINABILITY
Melting Point 245°C to 249°C
Quantity 5 g
Beilstein 3624116
Merck Index 14,4719
Solubility Information Very soluble in water and methanol. Soluble in ethanol.
Formula Weight 184.07
Percent Purity ≥98%
Chemical Name or Material Histamine dihydrochloride

RUO – Research Use Only

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