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Harmine, 98+%
Beskrivelse
Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.
Solubility
Soluble in DMSO (100 mM), DMF (∼1.5 mg/ml), ethanol (∼1.5 mg/ml), and PBS (pH 7.2, ∼0.25 mg/ml). Insoluble in water.
Notes
Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.
Tekniske data
Tekniske data
| Kemisk navn eller materiale | Harmine |
| Smeltepunkt | 262°C to 266°C |
| Lugt | Odorless |
| Mængde | 250 mg |
| Beilstein | 178813 |
| Merck Index | 14,4616 |
| Opløselighedsinformation | Soluble in DMSO (100 mM),DMF (∽1.5mg/ml),ethanol (∽1.5mg/ml),and PBS (pH 7.2,∽0.25mg/ml). Insoluble in water. |
| Formel vægt | 212.25 |
| Procent renhed | ≥98% |
RUO – Research Use Only
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