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Tocris Bioscience™ H 151
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Artikelnummer. 18769306
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50 mg
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18769306 50 mg
18717606 10 mg
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Artikelnummer. 18769306 Leverandør Tocris Bioscience™ Leverandørnr. 6675/50

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Descripción

STING antagonist

H 151 is a STING antagonist. Covalently binds STING at Cys91, blocking palmitoylation and preventing assembly of STING clusters. Decreases inflammatory cytokine production in human and mouse cells in vitro. Also blocks CMA (Cat. No. 6677) -induced increases in levels of inflammatory cytokines in mice, and alleviates systemic inflammation in a mouse model of autoinflammatory disease.
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Especificaciones

Kemisk navn eller materiale N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
CAS 941987-60-6
Synonym ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
Mængde 50 mg
Mål STING Antagonists
Molekylær formel C17H17N3O
Formel vægt 279.34
Renhed 98%
Título del producto
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