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H 1152 dihydrochloride, Tocris Bioscience™ Product Code.: 30001317
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H 1152 dihydrochloride, Tocris Bioscience™
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Product Code. 30001317
1 mg, 1mg
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Quantity:
1 mg
Unit Size:
1mg
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Product Code. 30001317

Brand: Tocris Bioscience 2414/1

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This item is not returnable. View return policy

Description

Selective Rho-kinase (ROCK) inhibitor

Rho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 ÎĽM for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK respectively). Inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats.

Glycyl Derivative also available.

Greener Choice Claims
  • Environmental benefits include:
    • Ozone-Safe or Safe for the Ozone Layer
TRUSTED_SUSTAINABILITY

Specifications

CAS 871543-07-6
Molecular Formula C16H23Cl2N3O2S
Quantity 1 mg
Synonym h-1152 dihydrochloride, c16h21n3o2s.2hcl, s-+-2-methyl-1-4-methyl-5-isoquinolinyl sulfonyl-hexahydro-1h-1,4-diazepine dihydrochloride, brd7446 dihydrochloride, h 1152 dihydrochloride, dimethyl fasudil dihydrochloride, s-h-1152 dihydrochloride, s-h-1152 hydrochloride, s-2-methyl-1-4-methylisoquinoline-5-sulfonyl-1,4-diazepane dihydrochloride
InChI Key BFOPDSJOLUQULZ-GXKRWWSZSA-N
SMILES CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C.Cl.Cl
IUPAC Name 4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline;dihydrochloride
Molecular Weight (g/mol) 392.339
PubChem CID 11560225
Formula Weight 392.34
Percent Purity >98%
Chemical Name or Material H 1152 dihydrochloride
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