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  6. GSK3368715 dihydrochloride, MedChemExpress

GSK3368715 dihydrochloride, MedChemExpress

Product Code. 16491309
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Product Code. 16491309 Supplier Medchem Express Supplier No. HY128717A

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Description

MedChemExpress GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)).

GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity.

Specifications

Kemisk navn eller materiale GSK3368715 dihydrochloride
Fysisk form Powder
CAS 1628925-77-8
Farve White
Mængde 1 mg
Renhedsgrad noter Research
Molekylær formel C20H40Cl2N4O2
Til brug med (applikation) Cancer-programmed cell death
Synonym EPZ019997 dihydrochloride
Opløselighedsinformation DMSO : 230 mg/mL (523.37 mM; Need ultrasonic) ∣H2O : 140 mg/mL (318.57 mM; Need ultrasonic)
SMIL CNCCN(CC1=CNN=C1C2CCC(COCC)(COCC)CC2)C.Cl.Cl
Molekylvægt (g/mol) 439.46
Formel vægt 439.46
Procent renhed 99.66%
Grad Research
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Research purposes only

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