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Invitrogen™ GRB2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA517692
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Beskrivelse
It is not recommended to aliquot this antibody.
GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.
Tekniske data
| GRB2 | |
| Polyclonal | |
| Unconjugated | |
| GRB2 | |
| AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 100769627, 14784, 2885, 535298, 81504 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 217 μg/mL | |
| 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
| P62993, P62994, Q60631 | |
| GRB2 | |
| Synthetic peptide corresponding to carboxy-terminal residues of human GRB2. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Monkey, Bovine, Hamster | |
| Antibody | |
| IgG |
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