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STEMCELL Technologies Gö6983

Artikelnummer. 17120072
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17120072 1 mg
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Artikelnummer. 17120072 Leverandør STEMCELL Technologies Leverandørnr. 72462

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Description

PKC inhibitor

  • Gö6983 inhibits several isoforms of protein kinase C (PKC; IC50 = 7, 7, 6, 10, 60, and 20,000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ, and PKCμ, respectively) (Gschwendt et al.)
  • Enhances reprogramming of mouse embryonic fibroblasts to induced pluripotent stem cells (Dutta et al.)
  • Direct lineage reprogramming of fibroblasts to mature neurons, in combination with CHIR99021, RepSox, Forskolin, SP600125, VaLproic Acid, and Y-27632 (Hu et al.)
  • Inhibits differentiation and maintains pluripotency in mouse embryonic stem cells (Dutta et al.)
  • Enhances human ground state pluripotent stem cell viability and growth (Gafni et al.)
  • Inhibits proliferation of human primary fetal bone cells (Krattinger et al.)
  • Inhibits the formation of protoplatelets from megakaryocytes derived from adult mouse bone marrow (Williams et al.)

Specifications

CAS 133053-19-7
Synonym Gö 6983
Mængde 1 mg
Molekylær formel C26H26N4O3
Renhed ≥98%
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