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GNF-7, MedChemExpress

Artikelnummer. 16477017
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Artikelnummer. 16477017 Leverandør Medchem Express Leverandørnr. HY10943

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Beskrivelse

MedChemExpress GNF-7 is a multikinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC50s of 133 nM and 61 nM for Bcr-AblWT and Bcr-AblT315I, respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 kinase 1) and GCK (germinal center kinase) with IC50s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies.

GNF-7 is a multikinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC50s of 133 nM and 61 nM for Bcr-AblWT and Bcr-AblT315I, respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 kinase 1) and GCK (germinal center kinase) with IC50s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies.

Tekniske data

Kemisk navn eller materiale GNF-7
CAS 839706-07-9
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C28H24F3N7O2
Mængde 5 mg
Opløselighedsinformation DMSO : ≥ 33 mg/mL (60.27 mM)
SMIL O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC=C(C)N=C4)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5
Molekylvægt (g/mol) 547.53
Formel vægt 547.53
Procent renhed 98.93%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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