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Glypican 3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA513360

Additional Details : Weight : 0.01000kg

Product Code. 10008109

  • 4010.00 DKK / 0.10mg
Estimated Shipment: 26-06-2024
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Description

Description

GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
Specifications

Specifications

Glypican 3
Polyclonal
Unconjugated
GPC3
defective in Simpson-Golabi-Behmel overgrowth syndrome; DGSX; glypican 3; glypican proteoglycan 3; glypican-3; Glypican-3 alpha subunit; Glypican-3 beta subunit; Gpc3; GTR22; GTR2-2; heparan sulphate proteoglycan; intestinal protein OCI-5; MXR7; OCI5; OCI-5; proteoglycan GPC3; SDYS; secreted glypican-3; SGB; SGBS; SGBS1
Rabbit
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
14734, 2719
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Immunocytochemistry, Western Blot
2 mg/mL
PBS with 0.09% sodium azide
P51654, Q8CFZ4
GPC3
KLH conjugated synthetic peptide between 529-560 amino acids from the C-terminal region of human Glypican 3 (GPC3)
400 μL
Primary
Human, Mouse
Antibody
IgG
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