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Tocris Bioscience™ Genistein
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Product Code. 18702704
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Mængde:
10 mg
50 mg
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Product Code. Mængde
18702704 10 mg
18712804 50 mg
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Product Code. 18702704 missing translation for 'mfr' Tocris Bioscience™ missing translation for 'supplierNo' 1110/10

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Description

EGFR kinase inhibitor. Also estrogen and PPARγ ligand

Genistein is a phytoestrogen with a wide range of biological actions. Genistein inhibits protein tyrosine kinases including epidermal growth factor receptor kinase, binds to PPARγ and estrogen receptors and acts as an agonist at GPER. Genistein inhibits aggregation and fibrilization of Aβ42 and amylin37 (hiAPP). In Huntington's disease fibroblast cells, Genistein reduces intracellular mutant huntingtin (mHTT) aggregates and induces degradation of mHTT; in a cellular model of Huntington's disease, Genistein corrects the mutant phenotype through stimulation of autophagy.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 446-72-0
Molekylær formel C15H10O5

Specifications

Kemisk navn eller materiale Genistein
Mængde 10 mg
Formel vægt 270.24
Renhed >98%
Molekylvægt (g/mol) 270.24
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