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Description
GDC-0152 is a potent IAPs inhibitor, and binds to the BIR3 domains of XIAP, cIAP1, cIAP2 and the BIR domain of ML-IAP with Ki values of 28 nM, 17 nM, 43 nM and 14 nM, respectively.
Specifications
Specifications
Chemical Name or Material | GDC-0152 |
CAS | 873652-48-3 |
Color | White |
Purity Grade Notes | Research |
Molecular Formula | C25H34N6O3S |
Quantity | 10 mg |
Solubility Information | DMSO : ≥ 100 mg/mL (200.55 mM) ∣Ethanol : 50 mg/mL (100.27 mM; Need ultrasonic) |
SMILES | O=C(N1[C@H](C(NC2=C(C3=CC=CC=C3)N=NS2)=O)CCC1)[C@H](C4CCCCC4)NC([C@H](C)NC)=O |
Molecular Weight (g/mol) | 498.64 |
Formula Weight | 498.64 |
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Research purposes only
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Product Title
GDC-0152, MedChemExpress
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