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Tocris Bioscience™ FTBMT
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Artikelnummer. 18726566
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25 mg
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Artikelnummer. Mængde
18726566 25 mg
18725836 5 mg
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Artikelnummer. 18726566 Leverandør Tocris Bioscience™ Leverandørnr. 6784/25

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Beskrivelse

Potent and selective GPR52 agonist; orally bioavailable and BBB permeable

FTBMT (also known as TP 024) is a potent and selective GPR52 agonist (EC50 = 75 nM, Emax = 122%), which is selective for GPR52 over a panel of 98 targets including D1, D2, AMPA and NMDA. FTBMT suppresses methamphetamine-induced hyperlocomotion in mice, and inhibits MK-801 -induced hyperactivity (model for acute psychosis), without causing catalepsy in mice. This compound is orally bioavailable and brain penetrant.
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Tekniske data

Kemisk navn eller materiale 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide
CAS 1358575-02-6
Mængde 25 mg
Molekylær formel C19H16F4N4O
Formel vægt 392.35
Renhed 98%
Produkttitel
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