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Invitrogen™ Human FRAP1 (mTOR), GST Tag Recombinant Protein

Artikelnummer. 10012913
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Mængde:
10 μg
Pakningsstørrelse:
Hver
Denne vare kan ikke returneres. Se returpolicy
Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™.

FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P42345
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris with 2mM DTT, 0.5mM EDTA, 50% glycerol, 150mM NaCl, 0.1% polysorbate 20 and no preservative; pH 7.5
Gen-id (Entrez) 2475
Molekylvægt (g/mol) 163.9 kDa
Navn Human FRAP1 (mTOR), GST Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 10 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias 2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS
Fælles navn mTOR
Gen symbol MTOR
KinaseFamily PIKK Kinase Family
Protein længde 1360-2549
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag GST-tag
Sekvens 1360-2549
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group Ser⁄Thr Kinases: Atypical
Forsendelsestilstand Dry Ice
Systemkompatibilitet LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
Målindgang mTOR, FRAP1
Target Gene FK506 binding protein 12-rapamycin associated protein 1
Udtrykssystem Insect cells
Protein familie Kinases & Inhibitors
Protein form Recombinant, Catalytic
Form Liquid
Protein undertype Serine/Threonine Kinases
Forskningskategori Signal Transduction, Drug Development, Oncology
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