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Anti-Human Foxp3 Staining Set APC, eBioscience™
Antibody Staining Kit
Brand: Invitrogen 77-5776-40
Indeholder:
- Fixation/Permeabilization Concentrate (4X) (cat. 00-5123): 30mL, store at 2-8°C. Avoid agitation.
- Fixation/Permeabilization Diluent (cat. 00-5223): 100mL, store at 2-8°C.
- Permeabilization Buffer (10X) (cat. 00-8333): 100mL, store at 2-8°C. Note: The 10X Permeabilization Buffer has a natural tendency to precipitate, however, its function is not affected by this. To clarify, the solution can be filtered after dilution to 1x working solution.
- Normal Rat Serum (cat. 24-5555): 100 μL, store at 2-8°C.
- Anti-Human Foxp3 APC (clone PCH101, cat. 17-4776): 25 tests, store at 2-8°C. Light-sensitive material.
Beskrivelse
This Anti-Human Foxp3 Staining Set contains the buffers and monoclonal antibody necessary to successfully stain and identify Foxp3+ cells. The PCH101 monoclonal antibody reacts with the amino terminus of human Foxp3, also known as FORKHEAD BOX P3, SCURFIN, and JM2. Foxp3 is a 49-55kDa protein and a member of the forkhead/winged-helix family of transcription factors. It was identified as the gene responsible for the X-linked lymphoproliferative disease observed in scurfy (sf) mice and in the human disorder, X-linked autoimmunity-allergic dysregulation syndrome (XLAAD). Constitutive expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg), and ectopic expression of Foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells.The PCH101 antibody crossreacts with rhesus, chimpanzee, and cynomolgus Foxp3. PCH101 recognizes a different epitope of Foxp3 than clones 236A/E7 and 150D/E4.
Tekniske data
| Foxp3 | |
| Monoclonal | |
| APC | |
| Rotte | |
| RUO | |
| Chimpanzee, Cynomolgus, ADN, Macaque, Abe, Non-human Primate, Rhesus abe | |
| IgG2a κ |
| Flow Cytometry | |
| PCH101 | |
| Forkhead Box P3, Scurfin, JM2 | |
| 1 sæt | |
| Primary | |
| Store at 2-8°C. Do not freeze. Light sensitive material. Use within 6 months of opening or by date indicated on the bottle. | |
| eBioscience |
Sikkerhed og håndtering
Produktidentifikator
Signalord
Farekategori
Faresætning
Sikkerhedssætning
Supplerende oplysninger
- Anti-Human Foxp3 Staining Set APC, eBioscience
Signalord
- Fare
Farekategori
- Carcinogenicitet Kategori 1B
- Kimcellemutaqenicitet Kategori 2
- Hudsensibilisering Kategori 1
- Specifik målorgantoksicitet efter enkelt eksponering Kategori 1
Faresætning
- H317-Kan forårsage allergisk hudreaktion.
- H341-Mistænkt for at forårsage genetiske defekter.
- H350-Kan fremkalde kræft.
- H370-Forårsager organskader.
Sikkerhedssætning
- P201-Indhent særlige anvisninger før brug.
- P260-Indånd ikke pulver/røg/gas/tåge/damp/spray.
- P261-Undgå indånding af pulver/røg/gas/tåge/damp/spray.
- P264-Vask grundigt efter brug.
- P280-Bær beskyttelseshandsker/beskyttelsestøj/øjenbeskyttelse/ ansigtsbeskyttelse.
- P302+P352-VED KONTAKT MED HUDEN: Vask med rigeligt vand/.
- P308+P311-VED eksponering eller mistanke om eksponering: Ring til en GIFTINFORMATION/læge/.
- P308+P313-VED eksponering eller mistanke om eksponering: Søg lægehjælp.
- P333+P313-Ved hudirritation eller udslet: Søg lægehjælp.
- P501b-Indholdet/beholderen bortskaffes i henhold til de lokale/regionale/nationale/internationale forskrifter.
Supplerende oplysninger
- MIXTURE LIST-Indeholder: Formaldehyde, Methanol
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Produkttitel
Må kun bruges til undersøgelsesformål. Må ikke anvendes ved diagnostiske procedurer.
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