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FOXP3 Monoclonal Antibody (FJK-16s), eFluor™ 660, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

1238.00 DKK - 3065.00 DKK

Specifications

Antigen FOXP3
Clone FJK-16s
Concentration 0.2 mg/mL
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15381920
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Affymetrix eBioscience
50-5773-80
25 μg
1238.00 DKK
25µg
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15391920
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Affymetrix eBioscience
50-5773-82
100 μg
3065.00 DKK
100µg
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Description

Description

Description: The FJK-16s antibody reacts with mouse, rat, dog, porcine, bovine and cat Foxp3 also known as FORKHEAD BOX P3, SCURFIN, and JM2; cross reactivity of this antibody to other proteins has not been determined. Foxp3, a 49-55 kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in 'scurfy' (sf) mice. Constitutive high expression of foxP3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells. Immunoblotting with FJK-16s antibody has mapped the epitope to amino acids 75-125 of the mouse Foxp3 protein. In the human, this region has been shown to be alternatively spliced at the mRNA level. Both the alternatively-spliced and non-spliced isoforms are present in the CD4+CD25+ subset of lymphocytes. Preliminary RT-PCR experiments have not revealed this alternatively-spliced isoform in mouse splenocytes, suggesting different gene regulation in the mouse and human. Please note that FJK-16s has been optimized for use with the Foxp3/Transcription Factor Buffer Staining Set (cat. 00-5523). The use of other fixation and staining buffers is not recommended. Applications Reported: This FJK-16s antibody has been reported for use in intracellular staining followed by flow cytometric analysis, and immunohistochemical staining of frozen tissue sections.

FOXP3 Monoclonal antibody specifically detects FOXP3 in Bovine, Canine, Feline, Mouse, Porcine, Rat samples. It is validated for Flow Cytometry, Immunohistochemistry (Frozen).
Specifications

Specifications

FOXP3
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
Foxp3
Primary
4° C, store in dark, DO NOT FREEZE!
Foxp3
FJK-16s
Flow Cytometry, Immunohistochemistry (Frozen)
eFluor 660
Rat
Bovine, Canine, Feline, Mouse, Porcine, Rat
Q99JB6
100037405, 20371, 317382, 444998, 491876, 506053
IgG2a κ
Affinity chromatography
Antibody
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